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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
12.12
Human Site:
T124
Identified Species:
19.05
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
T124
L
G
D
E
H
W
A
T
D
P
D
M
Y
L
Q
Chimpanzee
Pan troglodytes
XP_510301
627
67581
Q103
G
S
E
E
A
R
P
Q
S
C
L
V
G
S
A
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
T124
L
G
D
E
H
W
A
T
D
P
D
M
Y
L
Q
Dog
Lupus familis
XP_544614
968
105825
T411
L
G
D
E
H
W
A
T
D
P
D
M
Y
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
D125
G
D
D
Q
W
A
A
D
P
D
M
Y
L
Q
S
Rat
Rattus norvegicus
Q62829
544
60692
S20
A
P
P
L
R
M
N
S
N
N
R
D
S
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
G115
R
R
R
A
Q
S
L
G
L
L
E
D
E
R
G
Chicken
Gallus gallus
XP_426393
667
74767
D124
L
G
E
D
R
P
P
D
M
Y
L
Q
S
P
E
Frog
Xenopus laevis
NP_001082100
650
73749
G119
D
R
F
H
Q
E
N
G
M
S
E
V
R
V
R
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
D124
L
G
E
L
N
E
A
D
A
L
G
D
G
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
M115
A
P
G
A
H
P
M
M
S
H
G
P
G
M
M
Honey Bee
Apis mellifera
XP_001122147
624
70155
T100
T
E
N
G
L
P
K
T
S
T
V
A
R
S
N
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
P48
T
K
K
K
K
T
M
P
N
P
F
M
K
K
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
T275
S
S
P
P
K
K
Q
T
E
K
S
Y
Y
S
S
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
S273
S
S
F
R
H
S
A
S
F
S
S
A
E
Q
L
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
13.3
0
N.A.
0
13.3
0
26.6
N.A.
6.6
6.6
13.3
N.A.
P-Site Similarity:
100
20
100
100
N.A.
20
13.3
N.A.
6.6
33.3
26.6
40
N.A.
13.3
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
14
7
7
40
0
7
0
0
14
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
7
27
7
0
0
0
20
20
7
20
20
0
0
0
% D
% Glu:
0
7
20
27
0
14
0
0
7
0
14
0
14
0
7
% E
% Phe:
0
0
14
0
0
0
0
0
7
0
7
0
0
0
0
% F
% Gly:
14
34
7
7
0
0
0
14
0
0
14
0
20
0
7
% G
% His:
0
0
0
7
34
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
7
7
7
14
7
7
0
0
7
0
0
7
7
0
% K
% Leu:
34
0
0
14
7
0
7
0
7
14
14
0
7
20
7
% L
% Met:
0
0
0
0
0
7
14
7
14
0
7
27
0
7
7
% M
% Asn:
0
0
7
0
7
0
14
0
14
7
0
0
0
0
14
% N
% Pro:
0
14
14
7
0
20
14
7
7
27
0
7
0
7
0
% P
% Gln:
0
0
0
7
14
0
7
7
0
0
0
7
0
14
27
% Q
% Arg:
7
14
7
7
14
7
0
0
0
0
7
0
14
7
7
% R
% Ser:
14
20
0
0
0
14
0
14
20
14
14
0
14
27
14
% S
% Thr:
14
0
0
0
0
7
0
34
0
7
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
7
14
0
7
0
% V
% Trp:
0
0
0
0
7
20
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
14
27
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _